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SIRT3 correlates with immune infiltration and impacts immunotherapy efficacy for NSCLC patients

Ze Yu1, Hongtao Liao2, Guanhuai Wu2

  • 1Laboratory of Cytobiology & Molecular Biology, Zhoushan Hospital, Zhejiang University School of Medicine, Zhoushan, Zhejiang Province, China; Laboratory of Cytobiology & Molecular Biology, Zhoushan Hospital, Wenzhou Medical University, Zhoushan, Zhejiang Province, China.

Asian Journal of Surgery
|October 23, 2023
PubMed
Abstract

No abstract available in PubMed .

Keywords:
ICB responseImmune infiltrationNSCLCSIRT3

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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