[Apropos of a case of gastric pseudolymphoma]

The surprisingly long survival of patients with inoperable gastric lymphoma has led to the identification of pseudolymphoma, i.e. isolated or ulcer-related lymphoid reaction of an organ. We report six years follow-up of a patient suffering from a chronic gastric ulcer associated with lymphocytic follicular gastritis with germinal centers. The preoperative diagnosis of pseudolymphoma is difficult, since typical clinical signs as well as specific endoscopic and radiologic criteria are lacking. The diagnosis of pseudolymphoma can be established only on the basis of precise histological and immunochemical investigations. The association of lymphomatous foci with pseudolymphoma on gastrectomy specimens suggests the malignant potential of the lesion and its uncertain prognosis. Discovery of lymphomatous transformation by repeated biopsies is an indication for surgery.