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Updated: Jul 12, 2025

A Reversible Silicon Oil-Induced Ocular Hypertension Model in Mice
Published on: November 15, 2019
Surgical technique for removal of high-density silicone oil (Oxane HD)
Ramon Antunes De Oliveira1, Nilva Simeren Bueno De Moraes1, Rodrigo Antonio Brant Fernandes1
1Department of Ophthalmology, Universidade Federal de São Paulo (UNIFESP/EPM), São Paulo, Brazil.
Abstract:
The main drawback for the use of heavy silicone oil (HSO) Oxane HD is the difficulties it presents during removal. It differs from conventional silicone oil removal because it progressively concentrates in the posterior pole during the removal because of its heavier than water density. We describe a technique to facilitate proper HSO Oxane HD removal and minimize residual posterior bubbles and intraoperative complications. We describe our pearls for removing HSO to obtain the optimal results. A concern associated with HSO is the difficulty it presents when it is removed. However, this can be overcome by appropriate modification of surgical techniques during removal to limit intraoperative complications.

