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Updated: Jun 14, 2026

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Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
Published on: May 1, 2015
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Tracking the cellular immune response from early premalignancy to active multiple myeloma in a new model
Suchita Suryakant Jadhav1, Galia Luboshits1, Bjarne Bogen2
1Department Chemical Engineering & Biotechnology, Ariel University, Ariel, Israel.
European Journal of Immunology
|October 24, 2023
Abstract
None:
To calibrate a murine model to study premalignant to malignant multiple myeloma, mice were inoculated with different amounts of myeloma cells, and changes in the immune profile were tracked for over 200 days. The model highlights the development of T-cell exhaustion and suppressor before the appearance of clinical symptoms.

