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Neglected tropical disease (NTD) diagnostics: current development and operations to advance control
Oyetunde T Oyeyemi1,2, Olumide Ogundahunsi3, Mirjam Schunk4
1Department of Biosciences and Biotechnology, University of Medical Sciences, Ondo, Nigeria.
Pathogens and Global Health
|October 24, 2023
Summary
Early diagnosis of neglected tropical diseases (NTDs) is crucial for effective intervention. Developing and deploying point-of-care NTD diagnostics, especially in resource-limited settings, is key to achieving global elimination goals.
Area of Science:
- Public Health
- Infectious Diseases
- Diagnostic Development
Background:
- Neglected tropical diseases (NTDs) pose significant global health challenges.
- Late diagnosis and management of NTDs contribute substantially to disease burden.
- Early diagnosis is vital for surveillance and effective intervention planning.
Purpose of the Study:
- To review common NTDs and advancements in their diagnostics.
- To identify strategies for improving NTD diagnosis and intervention deployment.
- To assess the role of point-of-care diagnostics in NTD control.
Main Methods:
- Literature review of common NTDs.
- Analysis of diagnostic development progress for NTDs.
- Evaluation of point-of-care diagnostic (POC-NTD) tool potential and challenges.
Main Results:
- Progress in NTD diagnostic development is noted.
- Point-of-care NTD (POC-NTD) diagnostics are recommended for resource-limited areas.
- Commercial availability of POC-NTD tools remains limited.
- Training healthcare workers on POC-NTD use and psychosocial impacts is critical.
Conclusions:
- Leveraging technology and improving operational deployment of diagnostics are essential for the 2030 NTD elimination target.
- POC-NTD diagnostics offer promise for mapping risk zones and monitoring treatment, but require further development and accessibility.
- Addressing healthcare worker training needs and considering the impact of pandemics like COVID-19 on NTD programs are crucial for strengthening health systems and achieving elimination goals.
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