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Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
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Appendicitis-II: Diagnostic Studies and Management01:29

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
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The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Inflammatory Bowel Disease V: Surgical Management01:21

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
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Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
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Appendicitis Caused by a Giant Appendicolith.

Christos Tepelidis1, Athanasios Permekerlis1, Panagiotis Fotiadis1

  • 12nd Surgical Department, 424 General Military Hospital, Thessaloniki, GRC.

Cureus
|October 24, 2023
PubMed
Summary
This summary is machine-generated.

Giant appendiceal coproliths, fecal impactions over 2cm, can cause acute appendicitis. This case highlights their role in perforation and the importance of prompt surgical treatment for better outcomes.

Keywords:
acute peritonitisappendiceal perforationdiagnosis of acute appendicitisgiant appendicolithrare case report

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Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Appendiceal coproliths are fecal remnants in the appendix lumen, classified by size (<1cm common, >2cm giant).
  • Acute appendicitis pathophysiology involves lumen obstruction, leading to distension, ischemia, and potential rupture.

Observation:

  • A 38-year-old male presented with acute right lower quadrant pain, tenderness, and elevated inflammatory markers.
  • Radiological imaging (X-ray, CT scan) identified a 2.5cm giant coprolith obstructing the appendix.

Findings:

  • The patient underwent exploratory laparoscopy, revealing appendix wall rupture and purulent collection.
  • Appendicectomy was performed, and the patient recovered well, discharged on postoperative day four.

Implications:

  • Giant appendiceal coproliths are a significant cause of acute appendicitis, associated with higher perforation and abscess risk.
  • Early diagnosis and surgical intervention for giant coprolith-induced appendicitis are crucial for favorable patient prognosis.