Optimized deep neural network models for blood pressure classification using Fourier analysis-based time-frequency

Pankaj1, Ashish Kumar2, Manjeet Kumar3

  • 1Department of Electronics and Communication Engineering, Bennett University, Greater Noida, India.

PubMed

Insights

This study estimates blood pressure (BP) from photoplethysmography (PPG) signals, even with motion artifacts. A deep neural network approach using Fourier decomposition achieved 96.5% accuracy in classifying hypertension, aiding cardiovascular disease prevention.

Area of Science:

  • Biomedical Engineering
  • Signal Processing
  • Artificial Intelligence

Background:

  • Cardiovascular diseases (CVDs) pose a significant health risk, with hypertension being a primary cause.
  • Effective blood pressure (BP) management through continuous monitoring and rapid diagnosis is crucial for CVD prevention.
  • Photoplethysmography (PPG) signals offer a non-invasive method for physiological monitoring, but are susceptible to motion artifacts.

Purpose of the Study:

  • To develop a real-time method for estimating BP from motion artifact-affected PPG signals.
  • To propose a deep neural network (DNN) methodology for accurate PPG signal classification.
  • To classify PPG signals into normotension, pre-hypertension, and hypertension categories.

Main Methods:

  • Utilizing the Fourier Decomposition Method (FDM) to transform PPG signals into time-frequency (TF) spectrograms.
  • Modifying the last three layers of pre-trained DNNs (GoogleNet, DenseNet, AlexNet) for PPG signal classification.
  • Training and testing the framework on MIMIC-III and PPG-BP databases using a five-fold cross-validation approach.

Main Results:

  • The proposed framework with the DenseNet-201 network achieved a test accuracy of 96.5%.
  • FDM effectively computed TF spectrograms, separating motion artifacts and noise from PPG signals.
  • DNNs trained with clean PPG signal features demonstrated improved generalized capability for real-time BP classification.

Conclusions:

  • The DNN-based approach using FDM-generated TF spectrograms accurately estimates BP from noisy PPG signals.
  • DenseNet-201 demonstrated superior performance in classifying BP states from PPG data.
  • This method enhances the potential for real-time, non-invasive BP monitoring and hypertension screening.

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