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Admix-kit: An Integrated Toolkit and Pipeline for Genetic Analyses of Admixed Populations
Kangcheng Hou1, Stephanie Gogarten2, Joohyun Kim3
1Bioinformatics Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA, USA.
Abstract:
Admixed populations, with their unique and diverse genetic backgrounds, are often underrepresented in genetic studies. This oversight not only limits our understanding but also exacerbates existing health disparities. One major barrier has been the lack of efficient tools tailored for the special challenges of genetic study of admixed populations. Here, we present admix-kit, an integrated toolkit and pipeline for genetic analyses of admixed populations. Admix-kit implements a suite of methods to facilitate genotype and phenotype simulation, association testing, genetic architecture inference, and polygenic scoring in admixed populations.
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