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Published on: July 5, 2017
Effect of intradialytic weight resistance training exercise in sarcopenic hemodialysis patients: A randomized
Chokchai Chaovarin1, Amnart Chaiprasert1, Bancha Satirapoj1
1Division of Nephrology, Department of Medicine, Phramongkutklao College of Medicine, Bangkok, Thailand.
Background:
Sarcopenia has a high prevalence in end-stage kidney disease (ESKD). However, there is limited evidence of resistance exercise in these patients.
Objective:
The study investigated the effects of resistance exercise on muscle mass, strength, and physical functioning.
Method:
Fifty-three patients were randomly assigned to resistance training exercise (n = 26) and standard exercise (n = 27) groups. All of the patients were diagnosed with sarcopenia by the Asian Working Group for Sarcopenia 2019 criteria.
Results:
After 12 weeks, an improvement in leg muscle strength was significantly greater in the resistant exercise group compared with standard exercise (12.19 vs. 2.83 kg, p < 0.001). Appendicular skeletal muscle mass had a mean difference (1.01 vs. 1.02 kg/m2 , p = 0.96). Physical performance status had a mean difference (-2.3 vs. -18 s, p = 0.42). There were no serious adverse events.
Conclusion:
Over a 12-week follow-up, resistance exercise improved muscle strength in sarcopenic ESKD patients. Muscle mass and physical performance showed no significant change, but there is still a trend demonstrating to improve.
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