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Updated: Jul 12, 2025

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

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Association between psoriasis and cardiometabolic comorbidities in a racially and ethnically diverse low-income

Nora Rudd1, Nathaly Gonzalez2, Michael A Kohn3

  • 1University of California, San Francisco (UCSF) - School of Medicine, San Francisco, CA, USA.

Clinical and Experimental Dermatology
|October 24, 2023
PubMed

Insights

Psoriasis links to obesity, diabetes, high cholesterol, and hypertension. These risks were similar across racial/ethnic groups in a diverse, low-income population, highlighting the need for interventions.

Area of Science:

  • Dermatology
  • Cardiology
  • Public Health

Background:

  • Psoriasis is linked to cardiometabolic diseases like obesity, diabetes, hyperlipidaemia, and hypertension.
  • Previous studies often excluded diverse or low-income populations, potentially limiting generalizability.

Purpose of the Study:

  • To investigate if psoriasis risk for cardiometabolic comorbidities differs across racial/ethnic minority groups.
  • To assess the role of race/ethnicity as an effect modifier in psoriasis-associated cardiometabolic conditions.

Main Methods:

  • Cross-sectional analysis of 56,987 low-income patients.
  • Stratified analysis by race/ethnicity to compare comorbidity prevalence in patients with and without psoriasis.
  • Statistical assessment for effect modification by race/ethnicity.

Main Results:

  • Psoriasis showed a significant association with obesity, diabetes, hyperlipidaemia, and hypertension.
  • No significant difference in these associations was observed across racial/ethnic groups, indicating no effect modification.
  • The study population exhibited a very high baseline prevalence of cardiometabolic comorbidities.

Conclusions:

  • Psoriasis is associated with significant cardiometabolic comorbidities across diverse racial/ethnic groups.
  • Interventions targeting modifiable risk factors are crucial, especially for vulnerable, low-income populations.
  • Further research is needed to understand the high comorbidity burden in these populations.

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