Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Biological Effects of Radiation

Biological Effects of Radiation

All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...

Radiation: Applications

Radiation: Applications

The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Erratum to 2025 American Association for Thoracic Surgery (AATS) Expert Consensus Document: Surgical management of acute myocardial infarction and associated complications: The Journal of Thoracic and Cardiovascular Surgery, Volume 170, Issue 5, 2025, Pages 1327-1344.

The Journal of thoracic and cardiovascular surgery·2026

Same author

Outcomes of In-hospital Cardiac Arrest: Insights from a Medical Intensive Care Unit.

PloS one·2026

Same author

Initial experience with transcatheter aortic valve replacement before and after lung transplant.

JTCVS structural and endovascular·2026

Same author

High-density lipoprotein cholesterol influences the outcomes of lung transplantation in females, but not males.

Respiratory medicine·2026

Same author

Machine Learning Based Prediction of Hospital Mortality in Post-Cardiotomy Cardiogenic Shock with Mechanical Support.

ESC heart failure·2026

Same author

Cardiac reoperations in patients with prior thoracic radiation: A single-center analysis of outcomes and key lessons.

The Journal of thoracic and cardiovascular surgery·2026

Same journal

Side Port Resistance Limits Distal Perfusion Flow.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026

Same journal

The HELP Score in Non-Asphyxial Hypothermic Cardiac Arrest Treated With Extracorporeal Life Support: External Validation and Clinical Utility.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026

Same journal

Incidence and Mortality Outcomes of Extracorporeal Membrane Oxygenation in Infants With Congenital Lung Malformations: A Registry Study.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026

Same journal

Hemolysis During Microaxial Flow Pump Support: Cause or Marker of Hemocompatibility-Related Adverse Events After Left Ventricular Assist Device Implantation?

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026

Same journal

Machine Learning Prediction of Pediatric In-Hospital Survival Before Extracorporeal Membrane Oxygenation Cannulation.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026

Same journal

Erratum: Safety and Efficacy of Stored Wet-Preprimed Extracorporeal Membrane Oxygenation Circuits: A Scoping Review.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 12, 2025

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis

Published on: August 31, 2022

Radiation Exposure in Extracorporeal Life Support.

Sudhir Krishnan¹, Edward Soltesz², Justin Hanks¹

¹From the Respiratory Institute, Cleveland Clinic, Cleveland, Ohio.

ASAIO Journal (American Society for Artificial Internal Organs : 1992)

|October 24, 2023

Summary

This summary is machine-generated.

Extracorporeal membrane oxygenation (ECMO) patients often receive high radiation doses, exceeding International Commission of Radiological Protection (ICRP) limits. Computer tomography and interventional radiology significantly contribute to this cumulative effective dose (CED).

More Related Videos

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Published on: January 17, 2025

Author Spotlight: Utilizing Next-Generation Polymerized Human Hemoglobin for Improved Donor Lung Evaluation and Preservation in Rats

Author Spotlight: Utilizing Next-Generation Polymerized Human Hemoglobin for Improved Donor Lung Evaluation and Preservation in Rats

Published on: June 14, 2024

Related Experiment Videos

Last Updated: Jul 12, 2025

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis

Published on: August 31, 2022

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Published on: January 17, 2025

Author Spotlight: Utilizing Next-Generation Polymerized Human Hemoglobin for Improved Donor Lung Evaluation and Preservation in Rats

Author Spotlight: Utilizing Next-Generation Polymerized Human Hemoglobin for Improved Donor Lung Evaluation and Preservation in Rats

Published on: June 14, 2024

Area of Science:

Radiology
Medical Physics
Critical Care Medicine

Background:

Extracorporeal membrane oxygenation (ECMO) necessitates frequent radiologic imaging.
Patient radiation exposure during ECMO is a growing concern, potentially exceeding established safety limits.

Purpose of the Study:

To evaluate the cumulative effective dose (CED) of ionizing radiation in adult ECMO patients.
To compare radiation exposure against International Commission of Radiological Protection (ICRP) recommendations.
To identify sources contributing to high radiation doses during ECMO and hospitalization.

Main Methods:

Retrospective observational study of 306 adult ECMO admissions (2016-2018).
Calculation of CED based on reference values for radiologic studies.
Analysis of radiation exposure during ECMO and entire hospitalization periods.

Main Results:

4.5% of patients exceeded the 5-year ICRP cumulative limit (100 mSv) during ECMO; 14.7% exceeded it over the entire hospitalization.
Median CED during ECMO was 2.3 mSv, contributing 13% to the median hospitalization CED of 17.4 mSv.
Computer tomography (CT) and interventional radiology (IR) accounted for over 88% of CED during ECMO and 89% during hospitalization.

Conclusions:

A significant proportion of ECMO patients receive substantial radiation doses, with CT and IR being major contributors.
Current radiation exposure levels highlight the need for revised guidelines and mitigation strategies for ECMO patients.
Longer hospitalization duration correlates with increased cumulative effective dose, emphasizing the importance of radiation management throughout the patient's stay.