[Recent advances in carbon dots-based chromatographic separation materials].

Area of Science:

• Separation Science
• Materials Science
• Nanotechnology

Context:

• Chromatographic separation relies heavily on the properties of stationary phase materials.
• Nanomaterials, particularly carbon dots (CDs), offer unique advantages due to their nanoscale size, large surface area, and tunable surface chemistry.
• Traditional chromatographic materials face limitations that novel nanomaterials aim to overcome.

Purpose:

• To review the development and application of carbon dots (CDs) as stationary phase materials in chromatography.
• To systematically analyze the preparation methods and performance of CDs-based stationary phases for various chromatographic techniques.
• To discuss the future prospects and research directions for CDs in chromatographic separation.

Summary:

• Carbon dots (CDs) are zero-dimensional fluorescent nanomaterials with simple preparation, low toxicity, and excellent biocompatibility.
• CDs possess abundant surface functional groups and moderate adsorption properties, making them ideal for chromatographic stationary phases.
• Their application as stationary phases in HPLC, GC, and CEC improves separation efficiency and avoids issues like peak-tailing.

Impact:

• CDs offer a promising alternative to traditional chromatographic materials, enhancing separation performance.
• This review provides insights into the rational design and application of CDs-based chromatographic materials.
• The findings can guide future research in developing advanced separation materials for diverse analytical applications.