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Related Concept Videos

External Anatomy of the Kidney01:21

External Anatomy of the Kidney

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The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
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Blood and Nerve Supply to the Kidney01:18

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The kidneys are vital organs responsible for filtering and cleaning blood, removing waste products, and regulating electrolyte levels. To perform these essential functions, they require a constant and robust blood supply.
Bloody Supply to the Kidneys:
The kidneys receive their blood supply from the renal arteries, which branch off from the abdominal aorta—the main artery supplying the abdomen and lower body. The renal arteries enter the kidneys at the hilum, a notch on the medial side of...
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Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

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Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
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Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

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Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
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Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

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Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
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Related Experiment Video

Updated: Jul 12, 2025

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
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Case Report: Primary osteosarcoma of the kidney.

Junyong Chen1, Hongxian Liao2, Rungen Zhan3

  • 1Department of Urology, Zhuhai People's Hospital (Zhuhai hospital affiliated to Jinan University), Zhuhai, China.

Frontiers in Oncology
|October 25, 2023
PubMed
Summary

Extraosseous osteosarcoma is a rare cancer. This case highlights a malignant tumor originating in the kidney, a location rarely affected by this condition.

Keywords:
CTMRIextraosseouskidneyosteosarcoma

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Area of Science:

  • Oncology
  • Radiology
  • Pathology

Background:

  • Extraosseous osteosarcoma is a rare malignant neoplasm.
  • It typically affects the thigh, upper limbs, and retroperitoneum.
  • Renal involvement is exceptionally uncommon.

Observation:

  • A 54-year-old female patient presented with a left kidney mass.
  • Computed Tomography (CT) and Magnetic Resonance (MR) imaging were utilized.
  • Imaging revealed a soft tissue mass originating from the left kidney.

Findings:

  • The patient was diagnosed with malignant extraosseous osteosarcoma of the left kidney.
  • This represents a rare occurrence of osteosarcoma in a renal location.

Implications:

  • This case expands the known anatomical distribution of extraosseous osteosarcoma.
  • It underscores the importance of considering rare differentials in renal masses.
  • Further research into renal osteosarcoma pathogenesis and treatment is warranted.