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Updated: Jul 12, 2025

Simultaneous Data Collection of fMRI and fNIRS Measurements Using a Whole-Head Optode Array and Short-Distance Channels
Published on: October 20, 2023
Low-cost, smartphone-based instant three-dimensional registration system for infant functional near-infrared
Yunjia Xia1,2, Kui Wang1,2, Addison Billing2,3
1University College London, HUB of Intelligent Neuro-Engineering, CREATe, Division of Surgery and Interventional Science, Stanmore, United Kingdom.
Significance:
To effectively apply functional near-infrared spectroscopy (fNIRS)/diffuse optical tomography (DOT) devices, a three-dimensional (3D) model of the position of each optode on a subject's scalp and the positions of that subject's cranial landmarks are critical. Obtaining this information accurately in infants, who rarely stop moving, is an ongoing challenge.
Aim:
We propose a smartphone-based registration system that can potentially achieve a full-head 3D scan of a 6-month-old infant instantly.
Approach:
The proposed system is remotely controlled by a custom-designed Bluetooth controller. The scanned images can either be manually or automatically aligned to generate a 3D head surface model.
Results:
A full-head 3D scan of a 6-month-old infant can be achieved within 2 s via this system. In testing on a realistic but static infant head model, the average Euclidean error of optode position using this device was 1.8 mm.
Conclusions:
This low-cost 3D registration system therefore has the potential to permit accurate and near-instant fNIRS/DOT spatial registration.
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