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Updated: Jul 12, 2025
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Creation of Cardiac Tissue Exhibiting Mechanical Integration of Spheroids Using 3D Bioprinting
Published on: July 2, 2017
10.3K
[4D bioprinting technology and its application in cardiovascular tissue engineering]
Yuxiang Huang1,2, Qi Li1,3, Wu Ye1,2
1College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou 310014, Zhejiang, China.
Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology
|October 25, 2023
Summary
4D bioprinting uses smart materials to create dynamic tissues that mimic the human body. This technology offers a new approach for cardiovascular tissue engineering, improving in vitro models.
Area of Science:
- Biomedical Engineering
- Regenerative Medicine
- Tissue Engineering
Context:
- Current 3D bioprinting creates static tissues, unlike dynamic in vivo human tissues.
- A need exists for in vitro techniques simulating dynamic biological processes for better tissue compatibility.
- 4D printing, an extension of 3D bioprinting, incorporates time and smart materials to achieve dynamic tissue properties.
Purpose:
- To explore the latest advancements and applications of 4D printing technology.
- To provide a reference for developing 4D printed cardiovascular tissues.
- To bridge the gap between static in vitro models and dynamic in vivo environments.
Summary:
- 4D printing utilizes smart materials that respond to stimuli, enabling printed constructs to change shape, performance, and function over time.
- This dynamic capability allows for the creation of more physiologically relevant engineered tissues.
- The focus is on cardiovascular applications, highlighting progress and potential uses.
Impact:
- 4D bioprinting offers a novel approach to engineer dynamic cardiovascular tissues.
- It enhances the simulation of in vivo conditions for improved tissue compatibility.
- This technology holds significant promise for cardiovascular research and clinical applications.
