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Oxygen-regulated post-translation modifications as master signalling pathway in cells.

Michael Batie1, Temitope Fasanya1, Niall S Kenneth1

  • 1Department of Biochemistry, Cell and Systems Biology, Institute of Molecular Systems and Integrative Biology, University of Liverpool, Liverpool, UK.

EMBO Reports
|October 25, 2023
PubMed
Summary

Cells adapt to low oxygen (hypoxia) by altering post-translational modifications (PTMs). This review details how oxygen levels directly and indirectly impact PTMs, crucial for cellular survival and adaptation.

Keywords:
2-oxoglutarate dioxygenasesPTMshydroxylationhypoxiamethylations

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