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Intrinsic epidermoid cyst of the brainstem in children-review and case report

Adib Saráty Malveira1, Marcos Devanir Silva da Costa2, Esdras Ismael Borrayo Flores2

  • 1Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo, Rua Napoleão de Barros, 715, 6th Floor, Zip Code: 04024-002, Sao Paulo, SP, Brazil. adibsaraty@hotmail.com.

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|October 25, 2023
PubMed

Insights

Intrinsic brainstem epidermoid cysts are rare pediatric tumors. Maximum surgical resection is key for functional preservation in these young patients.

Area of Science:

  • Neuroscience
  • Pediatric Neurosurgery
  • Oncology

Background:

  • Intrinsic brainstem epidermoid cysts are exceptionally rare congenital tumors.
  • These lesions present unique diagnostic and therapeutic challenges due to their location.

Observation:

  • A systematic review of pediatric brainstem epidermoid cysts was conducted.
  • Twenty-one cases were identified, with a mean patient age of 4.85 years.
  • Common symptoms included cranial nerve deficits and pyramidal tract signs.

Findings:

  • Cranial nerve VII palsy was the most frequent neurological deficit observed.
  • Gross total resection was the primary treatment modality in the presented case.
  • The study highlights the specific characteristics and clinical presentation of these rare tumors.

Implications:

  • Optimal treatment involves maximal safe resection to preserve neurological function.
  • Early diagnosis and surgical intervention are crucial for favorable outcomes.
  • Further research into the specific molecular mechanisms and long-term outcomes is warranted.
Abstract

Keywords:
ChildrenEpidermoid cystsEpidermoid surgical resectionIntrinsic brainstemPontomedullary

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