Related Experiment Videos
Antimicrobial and cytolytic activity of N,N-dimethyl-l-methyldodecylamine oxide
Folia Microbiologica
|January 1, 1979
Abstract:
N,N-Dimethyl-l-methyldodecylamine oxide inhibited the growth of bacteria, yeast and filamentous fungi; further it induced lysis of osmotically stabilized protoplasts of Saccharomyces cerevisiae and human erythrocytes. This effect is based evidently on a change in the organization and function of cell membranes.
Insights
N,N-Dimethyl-l-methyldodecylamine oxide, a chemical compound, effectively inhibits microbial growth, including bacteria, yeast, and fungi. It also causes cell membrane disruption in yeast and human red blood cells.
Area of Science:
- Microbiology
- Biochemistry
- Cell Biology
Background:
- N,N-Dimethyl-l-methyldodecylamine oxide is a chemical compound with potential biological activity.
- Understanding its effects on microbial and cellular structures is crucial.
Purpose of the Study:
- To investigate the antimicrobial properties of N,N-Dimethyl-l-methyldodecylamine oxide.
- To determine its effects on cell membranes of microorganisms and human cells.
Main Methods:
- Assessing the growth inhibition of bacteria, yeast, and filamentous fungi.
- Inducing lysis of osmotically stabilized protoplasts of Saccharomyces cerevisiae and human erythrocytes.
Main Results:
- N,N-Dimethyl-l-methyldodecylamine oxide demonstrated significant inhibition of bacterial, yeast, and fungal growth.
- The compound induced lysis in Saccharomyces cerevisiae protoplasts and human erythrocytes.
Conclusions:
- N,N-Dimethyl-l-methyldodecylamine oxide exhibits broad-spectrum antimicrobial activity.
- Its mechanism of action involves altering cell membrane organization and function.