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Published on: March 27, 2018
National trends in emergency coronary artery bypass grafting
William B Keeling1, Jose Binongo2, Jane Wei2
1Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, GA, USA.
Insights
Emergency coronary artery bypass grafting (CABG) volumes declined nationally. While overall mortality risk decreased, emergency salvage CABG showed increased mortality, suggesting current risk prediction models may be inadequate.
Area of Science:
- Cardiovascular Surgery
- Public Health
- Health Services Research
Background:
- Emergency coronary artery bypass grafting (CABG) is a critical but understudied procedure.
- Understanding national trends in emergency CABG is essential for assessing healthcare resource allocation and patient outcomes.
Purpose of the Study:
- To examine national trends in the volume and outcomes of emergency and emergency salvage coronary artery bypass grafting (CABG) procedures in the United States.
Main Methods:
- Analysis of the Society of Thoracic Surgeons national adult cardiac surgical database (2005-2017).
- Inclusion of 92,607 patients undergoing emergency and emergency salvage isolated CABG.
- Utilized generalized linear mixed models to assess time trends, accounting for regional clustering.
Main Results:
- A decline in annual emergency and emergency salvage CABG volumes from 7991 to 6916 cases.
- Overall predicted risk of mortality (PROM) decreased from 12% to 8%, with reduced postoperative morbidities.
- Observed-to-expected mortality ratios increased for emergency salvage CABG (1.16 to 1.66), with an average mortality rate of 46.5% in these cases.
Conclusions:
- National volumes of emergency and emergency salvage CABG have decreased.
- Increased mortality in emergency salvage CABG cases is a significant concern.
- Current PROM algorithms may not accurately assess the risk for emergency salvage CABG patients.
Objectives:
Emergency coronary artery bypass grafting (CABG) is often omitted from current research, and volumes as well as outcomes are unknown. The purpose of this research is to examine national trends in emergency CABG.
Methods:
The Society of Thoracic Surgeons national adult cardiac surgical database was queried from 2005 to 2017 for patients who underwent emergency and emergency salvage isolated CABG procedures, and 92 607 patients were included for analysis. Generalized linear mixed models were used to assess time trends, taking into account the clustering effect of region.
Results:
Over the study period, volumes of emergency and emergency salvage CABG declined from 7991 to 6916 cases/year. Emergency and emergency salvage cases accounted for ∼4.9% of all CABG procedures performed nationwide in 2005 and 4.1% in 2017. The predicted risk of mortality (PROM) declined in the entire patient cohort over time from 12% to 8% (P < 0.0001). Rates of important postoperative morbidities also declined including prolonged intubation, re-exploration for haemorrhage and postoperative pneumonia (P < 0.001). Observed-to-expected mortality rates rose over the study period from 0.81 to 1.06 as the overall PROM declined from 9.3% to 7.6%. Emergency salvage CABG rates also declined over the course of the study from 358 to 323 cases/year. The observed-to-expected ratios for mortality increased for emergency salvage CABG during the study from 1.16 to 1.66, and emergency salvage mortality rates averaged 46.5%.
Conclusions:
The volume of patients undergoing emergency and emergency salvage CABG in the USA has declined. Increases in mortality are largely driven by emergency salvage cases, and the PROM algorithm may not accurately reflect the risk involved for these patients.
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