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Use of Arabidopsis eceriferum Mutants to Explore Plant Cuticle Biosynthesis
Published on: May 31, 2008
An Arabidopsis mutant line lacking the mitochondrial calcium transport regulator MICU shows an altered metabolite
Emilia R Gutiérrez-Mireles1, José Carlos Páez-Franco2, Raúl Rodríguez-Ruíz1
1Departamento de Bioquímica, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad de México, México.
Abstract:
Plant metabolism is constantly changing and requires input signals for efficient regulation. The mitochondrial calcium uniporter (MCU) couples organellar and cytoplasmic calcium oscillations leading to oxidative metabolism regulation in a vast array of species. In Arabidopsis thaliana, genetic deletion of AtMICU leads to altered mitochondrial calcium handling and ultrastructure. Here we aimed to further assess the consequences upon genetic deletion of AtMICU. Our results confirm that AtMICU safeguards intracellular calcium transport associated with carbohydrate, amino acid, and phytol metabolism modifications. The implications of such alterations are discussed.
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