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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Computer Vision

Background:

  • Generative adversarial networks (GANs) offer superior data generation for medical imaging.
  • GANs are increasingly applied in image reconstruction, segmentation, detection, classification, and cross-modality synthesis.
  • A review of GANs in medical imaging is beneficial for researchers.

Purpose of the Study:

  • To review the origin, principles, and extended forms of GANs.
  • To summarize state-of-the-art GAN-based medical image processing methods.

Main Methods:

  • Literature search on Google Scholar and PubMed.
  • Keywords: Segmentation, Classification, medical image, generative adversarial network.
  • Screening of 5423 publications, with 121 studies included in the final analysis.

Main Results:

  • Review covers GAN applications from January 1, 2017, to present.
  • 121 studies analyzed across seven areas: synthesis, classification, segmentation, conversion, reconstruction, denoising, and lesion detection.
  • Studies categorized by clinical applications, classification methods, and imaging modalities.

Conclusions:

  • GANs effectively address limited training data for medical image diagnostic models.
  • GANs show promise in advancing medical image augmentation.
  • Future research should focus on GAN challenges: pattern collapse, instability, and interpretability.