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Related Experiment Video

Updated: Jul 12, 2025

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

How we manage a high D-dimer.

Massimo Franchini¹, Daniele Focosi², Mario Piergiulio Pezzo¹

¹Department of Transfusion Medicine and Hematology, Carlo Poma Hospital, Mantova, Italy.

|October 26, 2023

Summary

This summary is machine-generated.

Elevated D-dimer levels, a marker of blood clot breakdown, can occur in many conditions beyond venous thromboembolism (VTE). This review guides hematologists in managing patients with high D-dimer without VTE symptoms.

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Last Updated: Jul 12, 2025

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

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Published on: February 10, 2023

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug

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Published on: June 4, 2021

Area of Science:

Hematology
Coagulation Science
Biomarker Research

Background:

D-dimer is a key biomarker for coagulation activation and fibrinolysis.
It is routinely used in diagnosing and managing venous thromboembolism (VTE).
Elevated D-dimer levels can also result from non-thrombotic conditions like aging, pregnancy, and various diseases.

Conclusions:

Hematologists frequently encounter patients with elevated D-dimer without apparent thrombosis.
A systematic approach is necessary to differentiate VTE from other causes of elevated D-dimer.
This review offers a framework for managing such cases effectively.