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Related Concept Videos

Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

284
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
284
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

167
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
167
Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

216
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
216
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

459
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
459
Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

186
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
186
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

192
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
192

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Related Experiment Video

Updated: Jul 12, 2025

Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
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[Irritable bowel syndrome].

Lisa Vork1,2, Zlatan Mujagic3, Ad A M Masclee3

  • 1Catharina Ziekenhuis, afd. Maag-, Darm- en Leverziekten, Eindhoven.

Nederlands Tijdschrift Voor Geneeskunde
|October 26, 2023
PubMed
Summary

Irritable bowel syndrome (IBS) is a common gut-brain disorder. This review covers IBS diagnosis, management, and treatment guidelines for primary care, emphasizing early diagnosis and patient education.

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Area of Science:

  • Gastroenterology
  • Gut-brain interaction disorders
  • Functional gastrointestinal disorders

Background:

  • Irritable bowel syndrome (IBS) is a prevalent gut-brain interaction disorder with complex pathophysiology.
  • Diagnosis relies on Rome IV criteria, with further investigations reserved for suspected organic conditions.
  • Primary care is the setting for IBS diagnosis and initial management.

Approach:

  • This review synthesizes the recently updated Dutch guideline and general practice standards for IBS.
  • It details diagnostic procedures, indications for secondary care referral, and evidence-based treatment options.
  • Emphasis is placed on patient education and shared decision-making.

Key Points:

  • IBS management is challenging due to heterogeneous presentations and subgroup-specific treatment efficacy.
  • Early positive diagnosis and comprehensive patient education are crucial for reducing disease burden.
  • Shared decision-making empowers patients and improves outcomes.

Conclusions:

  • Effective IBS management requires a thorough understanding of diagnostic criteria and treatment nuances.
  • Primary care physicians play a vital role in optimizing patient care and minimizing socioeconomic impact.
  • Adherence to updated guidelines ensures consistent and evidence-based clinical practice for IBS.