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Oral lactoferrin administration does not impact the diversity or composition of the infant gut microbiota in a

Luis González^1,2, Jose Luis Paredes Sosa¹, Susan Mosquito¹

¹Laboratorio de Genómica Microbiana, Facultad de Ciencias e Ingeniería, Universidad Peruana Cayetano Heredia , Lima, Peru.

Microbiology Spectrum

|October 26, 2023

Abstract

Importance:

Previous studies have suggested that oral lactoferrin enhances diversity in the gut microbiota in infants while inhibiting the growth of opportunistic pathogens. However, the effect of lactoferrin on infant gut microbiota over time has yet to be thoroughly studied. Our study suggests that lactoferrin oral treatment in infants aged 12-18 months does not affect gut microbiome diversity and composition over time. To our knowledge, this is the first study to report the effect of lactoferrin on infant gut microbiome composition over time and helps elucidate its impact on infant health and its therapeutic potential.

Keywords:

16S rRNA sequencing Peru early life microbiome gut microbiota lactoferrin

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