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    Area of Science:

    • Global Health
    • Immunization Programs
    • Vaccine Coverage Trends

    Background:

    • The Immunization Agenda 2030 (IA2030) is the global strategy for 2021-2030, aiming for universal vaccine benefits.
    • Key IA2030 goals include a 50% reduction in unvaccinated children (DTPcv1) and 90% coverage for three DTP-containing vaccine doses (DTPcv3).

    Purpose of the Study:

    • To review global, regional, and national immunization coverage trends up to 2022.
    • To assess progress towards IA2030 goals.
    • To document the impact of the COVID-19 pandemic on immunization programs.

    Main Methods:

    • Analysis of World Health Organization (WHO) and UNICEF immunization coverage estimates.
    • Review of data from global, regional, and national levels through 2022.

    Main Results:

    • Global DTPcv1 coverage increased to 89% in 2022, and DTPcv3 coverage to 84%, but both remain below 2019 levels.
    • 14.3 million children missed DTPcv1 in 2022, a decrease from 2021 but an increase from 2019, with most in low-income countries.
    • Immunization recovery in 2022 was uneven, particularly impacting low-income nations.

    Conclusions:

    • Global immunization recovery is occurring but requires urgent catch-up vaccinations for children who missed doses.
    • Strengthening immunization programs is crucial for resilience against future health crises.
    • Continued efforts are needed to restore and improve vaccine coverage to protect against preventable diseases.