Incorporation of leucine by mouse synovial cells in vivo

Following 3H-leucine administration, mouse synovium was examined autoradiographically at various postinjection times to determine whether the pattern of 3H-leucine utilization in vivo is comparable to that previously reported in vitro. Synovial cells incorporated 3H-leucine in significantly greater amounts than other cells examined. The pattern suggested intracellular incorporation, followed by secretion.