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Updated: Jul 12, 2025

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
Acinetobacter baumannii Early-Onset Sepsis After Home Delivery Into Toilet Water
Patrícia Sousa1, Beatriz Sousa2, Francisca Calheiros-Trigo2
1Department of Pediatrics, Hospital Senhora da Oliveira, Guimarães, PRT.
Early-onset sepsis (EOS) in newborns can be caused by Acinetobacter baumannii, particularly in adverse birth situations. This case highlights the need to consider this pathogen in neonatal infections.
Area of Science:
- Neonatal Medicine
- Infectious Diseases
- Microbiology
Background:
- Early-onset sepsis (EOS) is a significant cause of neonatal morbidity and mortality.
- Pathogens are typically acquired during childbirth (intrapartum).
- Unsupervised pregnancies and home births present unique challenges.
Observation:
- A term neonate, born at home during an unsupervised delivery, developed culture-proven EOS.
- The causative agent was identified as Acinetobacter baumannii, a rare cause of neonatal sepsis.
- The neonate experienced severe thrombocytopenia and neutropenia during treatment.
Findings:
- Acinetobacter baumannii, though uncommon, can cause severe neonatal sepsis.
- The isolated strain was susceptible to all tested antibiotics.
- Treatment involved empirical and directed antibiotic therapy, including meropenem.
Implications:
- Raises awareness for Acinetobacter baumannii as a potential pathogen in neonatal sepsis.
- Emphasizes the importance of considering unusual pathogens in EOS, especially with adverse birth circumstances.
- Highlights the need for vigilance in managing neonatal infections in non-traditional birth settings.
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