Intratendinous Calcified Chondroid Mesenchymal Neoplasm: A Case Report
Christopher Warburton1, Richard Wang2, Kshitij Satnamdas Arora3
1Department of Orthopedics, University of Miami Miller School of Medicine, Miami, Florida.
Journal of Orthopaedic Case Reports
|October 27, 2023
Summary
This case report introduces calcified chondroid mesenchymal neoplasms (CCMN), a new tumor type. Imaging, particularly MRI, is key to differentiating CCMN from calcific tendinitis.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Calcified chondroid mesenchymal neoplasms (CCMN) represent a novel tumor category characterized by chondroid formation and specific gene fusions.
- Distinguishing CCMN from other conditions with similar imaging findings is clinically significant.
Observation:
- A 73-year-old female presented with hip and gluteal pain, initially misdiagnosed as calcific tendinitis.
- Imaging revealed a mass at the hamstring tendon origin with specific MRI signal characteristics and CT-identified calcifications and bone erosion.
- Histopathology confirmed calcium pyrophosphate crystal deposits and benign chondroid tissue, supporting the CCMN diagnosis.
Findings:
- CCMN exhibits overlapping imaging features with calcific tendinitis (calcium hydroxyapatite depositional disease).
- Contrast-enhanced MRI is crucial for differentiating CCMN from calcific tendinitis.
- This report details the multi-modal imaging characteristics of CCMN (radiography, CT, MRI).
Implications:
- Accurate diagnosis of CCMN is essential for appropriate patient management.
- Understanding the distinct imaging features of CCMN improves diagnostic accuracy.
- This work provides the first comprehensive description of CCMN imaging across multiple modalities.
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