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Investigating the Influence of High-Speed Gantry Rotation in Cardiac CT on Motion Artifacts in Aortic Stenosis

Guillaume Fahrni1, Giuseppe Gullo1, Aisha Touray1

  • 1Department of Diagnostic and Interventional Radiology, Lausanne University Hospital and University of Lausanne, Rue du Bugnon 46, 1011 Lausanne, Switzerland.

Journal of Cardiovascular Development and Disease
|October 27, 2023
PubMed

Insights

Faster gantry rotation in coronary CT angiography (CCTA) may reduce motion artifacts and improve diagnostic accuracy for coronary artery disease (CAD), potentially eliminating the need for beta-blockers.

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Medical Technology

Background:

  • Coronary CT angiography (CCTA) is vital for non-invasive coronary artery disease (CAD) assessment.
  • Motion artifacts can limit CCTA's clinical utility, often necessitating beta-blockers and slow heart rates.
  • Faster gantry rotation speeds (0.23 s/rot) offer potential but require validation in un-medicated patients.

Purpose of the Study:

  • To evaluate the impact of fast gantry rotation speed (0.23 s/rot) versus standard speed (0.28 s/rot) on CCTA.
  • To assess the influence of fast rotation on coronary motion artifacts and diagnostic accuracy for CAD.
  • To determine the added value of faster CCTA rotation in patients not premedicated with beta-blockers.

Main Methods:

  • A prospective, single-center, two-arm randomized controlled trial.
  • 142 patients aged ≥ 50 undergoing CCTA for aortic stenosis work-up were randomized.
  • Comparison of fast (0.23 s/rot) versus standard (0.28 s/rot) gantry rotation speeds.

Main Results:

  • The primary outcome is the rate of CCTAs with motion artifacts hindering interpretation.
  • Secondary outcomes include assessable coronary segments, diagnostic accuracy vs. invasive coronary angiography (ICA), motion artifact magnitude, CNR, and radiation dose.
  • Assessing if faster rotation improves image quality and diagnostic performance.

Conclusions:

  • FAST-CCT may reduce motion artifacts and enhance diagnostic quality.
  • This technology could potentially eliminate the need for heart rate control and beta-blocker administration.
  • Further research will clarify the clinical significance and patient safety of faster CCTA protocols.
Abstract

Keywords:
0.23CCTATAVIaortic stenosisbeta-blockersgantry rotation speedhigh-speedmotion artifactsprotocol

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