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Updated: Jul 12, 2025
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Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice
Published on: February 20, 2019
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Atherosclerosis Potential Drug Targets: Current Scenario and Future Perspectives
Omar Mohammed Ali Saleh Al Qarawani1, Palwinder Kaur1, Manish Vyas1
1Department of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, 144401, India.
Cardiovascular & Hematological Disorders Drug Targets
|October 27, 2023
Summary
Atherosclerosis remains a leading cause of death. New research explores cellular and molecular targets, including genetics and immune cells, to develop improved treatments for this widespread cardiovascular disease.
Area of Science:
- Cardiovascular Biology
- Molecular Medicine
Background:
- Atherosclerosis is a primary cause of morbidity and mortality globally, including in the US and Europe.
- Despite advances in diagnosis and early intervention, effective long-term management of atherosclerosis remains a challenge.
Purpose of the Study:
- To review the current understanding of atherosclerosis pathophysiology.
- To highlight emerging therapeutic strategies and targets for managing atherosclerosis.
- To discuss recent discoveries in cellular and molecular biology relevant to atherosclerosis treatment.
Main Methods:
- Literature review of current pathophysiological mechanisms.
- Analysis of limitations in existing therapeutic agents.
- Exploration of novel molecular and cellular targets.
Main Results:
- Conventional treatments for atherosclerosis have limitations.
- Emerging strategies show promise for more efficacious disease management.
- Genetic factors, immune cells, and non-coding RNA are key areas for future therapeutic development.
Conclusions:
- Further research into molecular and cellular mechanisms is crucial for advancing atherosclerosis therapeutics.
- Identifying new biomarkers and drug targets can lead to better pharmacological agents and delivery systems.
- Targeting genetic predispositions and immune responses offers a promising future direction for controlling atherosclerosis incidence and prevalence.
Keywords:
AtherosclerosisPCSK9 inhibitorsdyslipidemiafuture strategiesplaque formationtherapeutic interventions.More Related Videos
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