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Updated: Jul 12, 2025

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood
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Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood

Published on: October 2, 2019

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Impaired declarative memory consolidation in children with REM sleep-related obstructive sleep apnea

Yufen Tang1, Chao Yang2, Changming Wang3

  • 1Department of Respiratory Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.

Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine
|October 27, 2023
PubMed

Insights

Children with obstructive sleep apnea (OSA) during REM sleep show impaired memory consolidation. This highlights the importance of identifying specific OSA subtypes in pediatric memory development.

Area of Science:

  • Pediatric Sleep Medicine
  • Neuroscience
  • Cognitive Psychology

Background:

  • Obstructive sleep apnea (OSA) is prevalent in children and can affect cognitive functions.
  • Rapid eye movement (REM) sleep plays a crucial role in memory consolidation.
  • The impact of different OSA subtypes on declarative memory consolidation in children remains unclear.

Purpose of the Study:

  • To investigate declarative memory consolidation in children with REM sleep-related OSA (REM-OSA).
  • To compare memory consolidation across different OSA subtypes and healthy controls.
  • To examine correlations between memory consolidation and specific sleep-related respiratory parameters.

Main Methods:

  • Polysomnography and declarative memory testing were conducted in children aged 6-14 years.
  • Participants with snoring were classified into primary snoring (PS), NREM-OSA, SI-OSA, and REM-OSA groups.
  • Declarative memory consolidation was assessed using recall and recognition rates.

Main Results:

  • Children with REM-OSA exhibited lower recall consolidation compared to controls and NREM-OSA.
  • No significant correlations were found between memory consolidation and overall apnea-hypopnea index (OAHI) or NREM OAHI.
  • Recognition consolidation was negatively correlated with OAHI during REM sleep (OAHIREM).

Conclusions:

  • Declarative memory consolidation is impaired in children with REM-OSA.
  • Specific OSA subtypes, particularly REM-OSA, require attention due to their impact on memory.
  • Understanding OSA subtypes is crucial for addressing cognitive deficits in affected children.
Abstract

Keywords:
REM-OSAchildrenmemory consolidation

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