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Aseptic abscess associated with SAPHO syndrome: a case report
Chang Guk Kim1, Yeo Ju Kim2, Seunghun Lee1
1Department of Radiology, School of Medicine, Hanyang University Hospital, 222-1, Wangsimni-Ro Seongdong-Gu, Seoul, 04763, South Korea.
Skeletal Radiology
|October 27, 2023
Summary
Aseptic abscess (AA) is a rare autoinflammatory disorder presenting as sterile abscesses and inflammatory bowel disease. Steroid therapy is effective, unlike antibiotics, aiding diagnosis and treatment.
Area of Science:
- Rheumatology
- Dermatology
- Gastroenterology
Background:
- Aseptic abscess (AA) is a rare autoinflammatory condition.
- Characterized by sterile abscesses in various organs and associated inflammatory bowel disease.
- Distinguishing AA from infection is challenging due to similar radiological and histopathological findings.
Observation:
- A 56-year-old woman presented with aseptic abscess in the anterior chest wall.
- The patient also exhibited symptoms of synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome.
Findings:
- Steroid therapy demonstrated a positive response in managing the patient's condition.
- Antibiotic treatments were ineffective for the aseptic abscess.
Implications:
- This case highlights the importance of considering AA in patients with unexplained sterile abscesses.
- The co-occurrence with SAPHO syndrome suggests potential links between these autoinflammatory conditions.
- Accurate diagnosis and appropriate steroid treatment are crucial for managing aseptic abscesses.
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