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Management of Persistent, Post-adenotonsillectomy Obstructive Sleep Apnea in Children: An Official American Thoracic
Insights
Persistent obstructive sleep apnea (OSA) in children requires further management after initial surgery. This guideline offers evidence-based recommendations for clinicians treating children with ongoing pediatric OSA.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Clinical Practice Guidelines
Background:
- Obstructive sleep apnea (OSA) is a prevalent sleep disorder in children.
- Adenotonsillectomy is the primary treatment, but up to 40% of pediatric cases persist.
- This guideline addresses the management of persistent pediatric OSA.
Purpose of the Study:
- To provide an evidence-based clinical practice guideline for managing persistent pediatric obstructive sleep apnea (OSA).
- To guide clinicians, including physicians, dentists, and allied health professionals, in treating children with persistent OSA.
Main Methods:
- A multidisciplinary international expert panel convened to address key questions.
- Systematic literature review was conducted using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach.
- Recommendations considered evidence quality, benefits, risks, patient values, cost, and feasibility.
Main Results:
- Six distinct management options for persistent pediatric OSA were evaluated.
- Evidence-based recommendations were formulated for each management strategy.
Conclusions:
- The guideline provides recommendations for persistent pediatric OSA management, acknowledging limited evidence and relying on expert consensus.
- Future research priorities were identified for each recommendation to advance the field.
Abstract:
Background: Obstructive sleep apnea (OSA) is the most common sleep-related breathing disorder. Although adenotonsillectomy is first-line management for pediatric OSA, up to 40% of children may have persistent OSA. This document provides an evidence-based clinical practice guideline on the management of children with persistent OSA. The target audience is clinicians, including physicians, dentists, and allied health professionals, caring for children with OSA. Methods: A multidisciplinary international panel of experts was convened to determine key unanswered questions regarding the management of persistent pediatric OSA. We conducted a systematic review of the relevant literature. The Grading of Recommendations, Assessment, Development, and Evaluation approach was used to rate the quality of evidence and the strength of the clinical recommendations. The panel members considered the strength of each recommendation and evaluated the benefits and risks of applying the intervention. In formulating the recommendations, the panel considered patient and caregiver values, the cost of care, and feasibility. Results: Recommendations were developed for six management options for persistent OSA. Conclusions: The panel developed recommendations for the management of persistent pediatric OSA based on limited evidence and expert opinion. Important areas for future research were identified for each recommendation.
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