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Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures
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Subcorneal Pustular Dermatosis Following SARS-CoV-2 Infection.

Alyssa Iurillo1, Sara Yumeen2, Dillion Imbriano3

  • 1Indiana University School of Medicine, Indianapolis, IN.

Rhode Island Medical Journal (2013)
|October 27, 2023
PubMed
Summary
This summary is machine-generated.

Subcorneal pustular dermatosis (SPD), a rare skin condition, was observed following a SARS-CoV-2 infection. This case suggests a potential link between the viral illness and the onset of SPD, highlighting a new possible trigger for this dermatosis.

Keywords:
SPDSneddon–Wilkinson diseaseSubcorneal pustular dermatosis

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Area of Science:

  • Dermatology
  • Infectious Diseases
  • Immunology

Background:

  • Subcorneal pustular dermatosis (SPD), also known as Sneddon-Wilkinson disease, is a rare, recurrent pustular skin condition.
  • SPD is historically linked to conditions such as multiple myeloma, IgA gammopathy, pyoderma gangrenosum, and autoimmune disorders.

Observation:

  • A case of SPD developing subsequent to SARS-CoV-2 infection is presented.
  • The affected individual was a 52-year-old male.

Findings:

  • This report details the first documented instance of SPD occurring after SARS-CoV-2 infection.
  • The temporal association suggests SARS-CoV-2 may precipitate the onset of SPD.

Implications:

  • The findings suggest that viral infections, specifically SARS-CoV-2, could be a novel trigger for subcorneal pustular dermatosis.
  • Patients with SPD following SARS-CoV-2 infection may be at risk for future disease exacerbations, even during remission.