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Updated: Aug 4, 2026

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FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
Couple agreement before and after genetic counseling
American Journal of Medical Genetics
|November 1, 1986
Summary
Many couples seeking genetic counseling have differing concerns and reproductive plans. Post-counseling, agreement on reproductive plans and risk perception shows only marginal improvement, indicating persistent spousal disagreement.
Area of Science:
- Medical Genetics
- Psychology
- Family Studies
Background:
- Genetic counseling is sought by couples with diverse concerns and reproductive goals.
- Spousal concordance on reproductive plans and risk perception is crucial for effective genetic counseling outcomes.
Purpose of the Study:
- To assess pre- and post-counseling spousal agreement on major reasons for seeking genetic counseling, reproductive plans, and perceived risks.
- To evaluate the impact of genetic counseling on improving spousal concordance.
Main Methods:
- Administered identical questionnaires to 699 couples before and after genetic counseling.
- Assessed agreement on reasons for counseling, short-term and long-term reproductive plans, ideal number of children, perceived risk, and seriousness of potential problems.
Main Results:
- Before counseling, significant spousal disagreement existed regarding reasons for seeking help (55%), ideal number of children (40%), and risk perception (56%).
- Post-counseling, agreement improved for short-term plans (76%), longer-term plans (66%), and ideal number of children (60%), with statistically significant increases in risk interpretation and agreement on six potential problems.
- However, overall spousal disagreement persisted, with post-counseling agreement levels often similar to pre-counseling levels for several key issues.
Conclusions:
- Couples present to genetic counseling with substantial variation in concerns and reproductive intentions.
- Genetic counseling demonstrates a limited ability to significantly enhance spousal agreement on reproductive plans and risk perception.
- Counseling strategies may need refinement to address and reconcile differing spousal perspectives more effectively.
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