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Physical Activity, Inactivity and Sleep in Individuals with Hypertrophic Cardiomyopathy

Sarah J Charman1,2, Alasdair P Blain1, Nduka C Okwose1,2,3

  • 1Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom of Great Britain and Northern Ireland.

International Journal of Sports Medicine
|October 27, 2023
PubMed

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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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