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Related Concept Videos

Methods of Sterilization I: Physical Methods01:29

Methods of Sterilization I: Physical Methods

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As used in a healthcare facility, sterilization destroys all microorganisms through physical or chemical methods. The physical method includes steam, dry heat, boiling water, and radiation.
Steam sterilization uses non-toxic, low-cost moist heat in the form of saturated steam under pressure, which is fast, microbicidal, and sporicidal, and quickly warms and penetrates fabrics. Autoclaves, or steam sterilizers, expose each item to direct steam contact for a predetermined time at the necessary...
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Cleaning, Sterilization, and Disinfection01:30

Cleaning, Sterilization, and Disinfection

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Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
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Methods of Sterilization II: Chemical Methods01:30

Methods of Sterilization II: Chemical Methods

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In healthcare, the chemical method of sterilization uses chemical sterilants to treat surgical instruments and medical supplies to help prevent the transmission of infectious pathogens to patients. Due to heat sensitivity, most medical supplies and equipment should not be exposed to high temperatures. These parts include rubber, plastic, glass, and other similar elements.
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
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Physical Methods for Controlling Microbial Growth: Radiation and Filtration01:26

Physical Methods for Controlling Microbial Growth: Radiation and Filtration

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Radiation and filtration are essential tools for microbial control, targeting microorganisms through distinct mechanisms. Radiation eliminates microbes by damaging their DNA, either killing them or inhibiting their growth. Based on wavelength, radiation is classified into two types: nonionizing and ionizing radiation.Non-ionizing radiation, such as UV radiation (200–400 nm), is absorbed by DNA, causing defects that effectively disinfect surfaces, air, and water, including safety cabinets.
35
Physical Methods for Controlling Microbial Growth: Temperature01:23

Physical Methods for Controlling Microbial Growth: Temperature

31
Heat is a widely used method to control microbial growth by targeting and denaturing cellular proteins, thereby killing or inactivating microbes. This method's effectiveness is quantified using parameters such as the thermal death point (TDP), thermal death time (TDT), and decimal reduction time (D value). TDP represents the lowest temperature at which all microorganisms in a liquid suspension are eliminated within 10 minutes, whereas TDT is the time necessary to achieve sterilization at a...
31
Methods for Controlling Microbial Growth01:29

Methods for Controlling Microbial Growth

44
Microbial growth control refers to various methods employed to inhibit, reduce, or eliminate microorganisms to ensure safety and hygiene across different settings. These methods are categorized based on the target environment and the level of microbial control required.Biocides are versatile agents designed to control microorganisms by either inhibiting their growth or outright killing them. These agents work through various physical, chemical, mechanical, or biological mechanisms. The...
44

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Updated: Jul 12, 2025

The Portable Chemical Sterilizer PCS, D-FENS, and D-FEND ALL: Novel Chlorine Dioxide Decontamination Technologies for the Military
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The Portable Chemical Sterilizer PCS, D-FENS, and D-FEND ALL: Novel Chlorine Dioxide Decontamination Technologies for the Military

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Disinfection and sterilization: New technologies.

William A Rutala1, Curtis J Donskey2, David J Weber3

  • 1Statewide Program for Infection Control and Epidemiology, University of North Carolina (UNC) School of Medicine, Chapel Hill, NC; Division of Infectious Diseases, UNC School of Medicine, Chapel Hill, NC.

American Journal of Infection Control
|October 27, 2023
PubMed
Summary

New disinfection and sterilization technologies are emerging to combat challenging pathogens and complex medical devices, aiming to enhance patient safety and prevent cross-transmission of infections in healthcare settings.

Keywords:
New technology

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Area of Science:

  • Infection Control and Prevention
  • Medical Device Reprocessing
  • Microbiology and Emerging Pathogens

Background:

  • Proper disinfection and sterilization of medical devices are critical for preventing pathogen cross-transmission.
  • Emerging pathogens like Candida auris and complex medical devices present significant reprocessing challenges.

Purpose of the Study:

  • To identify and review novel disinfection and sterilization technologies.
  • To assess advancements in medical device reprocessing in light of new challenges.

Main Methods:

  • Comprehensive literature search using Google, Google Scholar, and PubMed.
  • Focused on published English articles detailing new disinfection and sterilization technologies.

Main Results:

  • Identified several innovative disinfection methods: electrostatic spraying, new sporicides, colorized disinfectants, and 'no-touch' or continuous room decontamination systems.
  • Discovered advancements in sterilization technologies, including new methods specifically for endoscopes.

Conclusions:

  • Emerging technologies offer promising solutions for reprocessing complex medical devices.
  • These advancements are expected to significantly reduce the risk of patient-to-patient pathogen transmission.