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Related Concept Videos

Hand hygiene01:23

Hand hygiene

3.3K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
3.3K
Surface Membrane Barriers01:18

Surface Membrane Barriers

1.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.1K
Chemical Agents for Microbial Control01:27

Chemical Agents for Microbial Control

38
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
38
Asepsis01:28

Asepsis

2.2K
The condition of being free from disease-causing living pathogens is asepsis. Aseptic techniques include a set of standard practices to achieve asepsis. An example is the regular environmental cleaning of all parts of the healthcare facility and hand hygiene at home before preparing or eating food. Medical and surgical asepsis in healthcare practice protects patients from harmful pathogens, minimizes the risk of contamination of susceptible sites, and reduces the risk of infection transmission.
2.2K
Cleaning, Sterilization, and Disinfection01:30

Cleaning, Sterilization, and Disinfection

6.9K
Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
6.9K
Defense Mechanism Against Infection01:26

Defense Mechanism Against Infection

6.5K
Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
6.5K

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Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

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What constitutes an adequate sample size for monitoring hand hygiene adherence?

American journal of infection control·2025
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Response to the comment on the article "No detrimental effect on the hand microbiome of health care staff by frequent alcohol-based antisepsis".

American journal of infection control·2025
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No detrimental effect on the hand microbiome of health care staff by frequent alcohol-based antisepsis.

American journal of infection control·2024
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Hand and environmental hygiene: respective roles for MRSA, multi-resistant gram negatives, Clostridioides difficile, and Candida spp.

Antimicrobial resistance and infection control·2024
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Rinse, gel, and foam - is there any evidence for a difference in their effectiveness in preventing infections?

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Disinfection, sterilization and antisepsis: An overview.

American journal of infection control·2023

Related Experiment Video

Updated: Jul 12, 2025

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics
08:30

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics

Published on: September 16, 2022

2.1K

Best products for skin antisepsis.

John M Boyce1

  • 1J.M. Boyce Consulting, LLC, Middletown, CT.

American Journal of Infection Control
|October 27, 2023
PubMed
Summary

Skin antiseptics are crucial for preventing infections before surgery and in high-risk patients. While progress is evident, optimizing skin preparation techniques remains essential for patient safety.

Area of Science:

  • Infection control and prevention
  • Surgical site infection (SSI) reduction
  • Healthcare-associated infection (HAI) management

Background:

  • Skin antiseptics are vital for surgical procedures and reducing infections in high-risk patients.
  • Current practices aim to minimize central line-associated infections and other HAIs.

Purpose of the Study:

  • To review and update evidence on skin antiseptic products and practices.
  • To identify areas for improvement in skin antisepsis protocols.

Main Methods:

  • A comprehensive PubMed search was conducted.
  • Evidence on skin antiseptic products and practices was systematically reviewed.

Main Results:

  • Guidelines recommend preoperative bathing but lack specifics on timing and chlorhexidine gluconate (CHG)-impregnated cloths.
Keywords:
CLABSI preventionDaily CHG bathingPre-operative bathingSkin antisepsisSurgical hand scrubSurgical site preparation

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  • Alcohol-based hand rubs show comparable or superior results to antimicrobial soaps for surgical hand antisepsis.
  • Daily CHG bathing in ICUs reduces CLABSIs, but evidence in non-ICUs is mixed; CHG monitoring is beneficial.
  • Alcohol-based products with 2% CHG reduce CLABSIs before central line insertion.

    • Conclusions:

    • Advancements in skin antisepsis products and protocols have been made.
    • Improvements in surgical site preparation techniques are still necessary.