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Updated: Jul 12, 2025
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Measurement of Carotenoids in Perifovea using the Macular Pigment Reflectometer
Published on: January 29, 2020
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The Effect of Beta-Carotene on Cognitive Function: A Systematic Review
Diana Marisol Abrego-Guandique1,2, Maria Luisa Bonet3,4,5, Maria Cristina Caroleo1,2
1Department of Health Sciences, University of Magna Graecia Catanzaro, 88100 Catanzaro, Italy.
Brain Sciences
|October 28, 2023
Summary
Beta-carotene, a vitamin A precursor, may support cognitive function, especially long-term. Supplementation combined with other nutrients shows promising benefits for brain health.
Area of Science:
- Nutrition Science
- Neuroscience
- Public Health
Background:
- Beta-carotene is a vital antioxidant and vitamin A precursor.
- Its role in cognitive function and mental health is under investigation.
- Existing research presents conflicting evidence on beta-carotene's efficacy.
Purpose of the Study:
- To systematically review the association between beta-carotene intake and cognitive performance.
- To clarify the effectiveness of beta-carotene, alone or combined with other nutrients, on cognitive health.
Main Methods:
- Systematic review adhering to PRISMA guidelines.
- Inclusion of 16 original research articles.
- Analysis of both epidemiological and intervention studies.
Main Results:
- Epidemiological studies (10) showed associations between beta-carotene levels and improved cognition (7/10).
- Short-term, isolated beta-carotene intake did not enhance cognitive function.
- Long-term intervention (18 years) and combined supplementation (with vitamins E, C, zinc, selenium) showed benefits.
Conclusions:
- Beta-carotene intake may be linked to cognitive function maintenance.
- Beta-carotene likely acts synergistically with other micronutrients.
- Further research is needed to fully elucidate beta-carotene's role in cognitive health.
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