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Comparison between Intravoxel Incoherent Motion and Splenic Volumetry to Predict Hepatic Fibrosis Staging in
Takayuki Arakane1, Masahiro Okada1, Yujiro Nakazawa1
1Department of Radiology, Nihon University School of Medicine, Tokyo 173-8610, Japan.
Diagnostics (Basel, Switzerland)
|October 28, 2023
Summary
Intravoxel incoherent motion (IVIM) and splenic volumetry (SV) show potential for predicting hepatic fibrosis (HF). SV/BSA is better for severe HF, while IVIM is more suitable for mild or no HF.
Area of Science:
- Radiology and Medical Imaging
- Hepatology
- Biophysics
Background:
- Hepatic fibrosis (HF) prediction is crucial for patient management.
- Intravoxel incoherent motion (IVIM) and splenic volumetry (SV) are emerging non-invasive techniques for assessing liver disease.
- Previous studies suggest IVIM and SV may be effective in predicting HF stages.
Purpose of the Study:
- To compare the efficacy of IVIM and SV in predicting hepatic fibrosis.
- To evaluate the correlation of IVIM indices and SV/BSA with pathological HF stages.
Main Methods:
- Sixty-seven patients with pathologically staged HF were included.
- IVIM parameters (D, D*, ADC, f) and SV/BSA were calculated and analyzed.
- Statistical analysis, including AUC, was performed to compare prediction capabilities.
Main Results:
- ADC and f showed a significant decrease with progressing HF, while SV/BSA increased.
- SV/BSA demonstrated higher predictive performance for severe HF (≥F3-4, ≥F4) compared to IVIM's f.
- IVIM's f showed higher predictive performance for mild or no HF (≤F0-1) than SV/BSA.
Conclusions:
- No significant overall difference was found between IVIM and SV/BSA in identifying HF.
- SV/BSA is a more effective tool for evaluating severe hepatic fibrosis.
- IVIM is more suitable for assessing mild or no hepatic fibrosis.
