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Sleep Disordered Breathing in Children with Neuromuscular Disease
Ambika G Chidambaram1, Sanjay Jhawar1, Craig M McDonald2
1Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, University of California, Davis, CA 95817, USA.
Children (Basel, Switzerland)
|October 28, 2023
Summary
Children with neuromuscular disease (NMD) experience high rates of sleep disordered breathing (SDB). Early diagnosis and management are crucial to prevent serious health issues.
Area of Science:
- Pediatric Pulmonology
- Neurology
- Sleep Medicine
Background:
- Sleep disordered breathing (SDB) is more common in children with neuromuscular disease (NMD).
- SDB can manifest as hypoventilation, hypoxemia, or various forms of sleep apnea.
- Sleep problems in NMD can be early indicators of the disease.
Purpose of the Study:
- To conduct a comprehensive literature review on SDB in children with NMD.
- To cover pathophysiology, clinical evaluation, diagnosis, and management of SDB in this population.
- To identify challenges in diagnosis and suggest future research directions.
Main Methods:
- Comprehensive literature review of SDB in pediatric NMD.
- Analysis of pathophysiological changes during sleep.
- Review of diagnostic challenges and management strategies.
Main Results:
- SDB is highly prevalent in pediatric NMD, presenting diverse symptoms.
- Polysomnography (PSG) is the gold standard but faces accessibility challenges for non-ambulatory patients.
- Untreated SDB significantly increases morbidity and mortality risks.
Conclusions:
- SDB is a critical concern in pediatric NMD requiring thorough evaluation.
- Addressing diagnostic and management challenges is essential for improving patient outcomes.
- Further research is needed to optimize SDB care in children with NMD.
Keywords:
hypoventilationneuromuscular diseasenon-invasive mode of ventilationobstructive sleep apneaMore Related Videos
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