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Frailty-Preventing Effect of an Intervention Program Using a Novel Complete Nutritional "COMB-FP Meal": A Pilot
Takuo Nakazeko1, Naohisa Shobako1, Nobuhiko Shioya2
1Future Food Research & Development Division, Nissin Foods Holdings Co., Ltd., Tokyo 192-0001, Japan.
Nutrients
|October 28, 2023
Summary
A new dietary intervention, the COMpletely Balanced for Frailty Prevention (COMB-FP) meal, improved walking speed and cognitive function in older adults. This nutritional approach shows promise for preventing frailty and promoting healthy aging.
Area of Science:
- Gerontology
- Nutritional Science
- Preventive Medicine
Background:
- Frailty is a significant health concern for the aging population.
- Dietary nutrition plays a crucial role in preventing aging and frailty.
Purpose of the Study:
- To evaluate a novel dietary intervention program, the COMpletely Balanced for Frailty Prevention (COMB-FP) meal, for frailty prevention.
- To compare the effects of exercise alone versus exercise combined with the COMB-FP meal program in individuals with pre-frailty or frailty.
Main Methods:
- A 12-week pilot randomized controlled trial involving 110 healthy volunteers with pre-frailty or frailty.
- The test group replaced two daily meals with COMB-FP meals, while the control group followed an exercise program only.
Main Results:
- The COMB-FP meal group showed significant improvements in walking speed and cognitive function compared to the control group.
- Positive trends were observed in frailty-related outcomes including microbiome occupancy, World Health Organization well-being index (WHO-5), and oxidative stress markers.
Conclusions:
- A well-balanced nutrient intake, as provided by the COMB-FP meal, is important for frailty prevention in the aging population.
- The COMB-FP dietary intervention shows potential as a strategy to mitigate frailty and support healthy aging.
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