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Related Experiment Video

Updated: Jul 12, 2025

Fabrication of Fine Electrodes on the Tip of Hypodermic Needle Using Photoresist Spray Coating and Flexible Photomask for Biomedical Applications
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A Planar-Type Micro-Biopsy Tool for a Capsule-Type Endoscope Using a One-Step Nickel Electroplating Process.

Sangjun Moon1,2,3

  • 1Department of Mechanical Convergence Engineering, Gyeongsang National University, Changwon 51391, Gyeongsangnam-do, Republic of Korea.

Micromachines
|October 28, 2023
PubMed
Summary
This summary is machine-generated.

Researchers developed novel electroplated nickel micro-biopsy tools for capsule endoscopes. These tools offer sharp tips and efficient tissue extraction for minimally invasive diagnosis and cancer biopsies.

Keywords:
capsule-type endoscopeone-step electroplatingplanar-type micro-biopsy tool

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Minimally Invasive Surgery

Background:

  • Millimeter-scale biopsy tools are common in minimally invasive surgery.
  • Capsule endoscopes require micro-scale biopsy tools with high precision.
  • Conventional machining is not cost-effective for micro-scale features.

Purpose of the Study:

  • To design and fabricate planar-type electroplated nickel micro-biopsy tools for capsule endoscopes.
  • To evaluate the performance of these micro-biopsy tools for in vitro tissue dissection.
  • To assess their suitability for clinical applications like cancer tissue biopsy.

Main Methods:

  • Utilized a thick photoresist (SU8) mold for one-step lithography.
  • Employed nickel electroplating to fabricate planar micro-biopsy tools.
  • Conducted in vitro tissue dissection experiments using mouse intestine.

Main Results:

  • Successfully fabricated micro-biopsy tools with sharp tips and planar shapes.
  • Evaluated various design features, including tip taper angle and scalpel geometry.
  • Demonstrated efficient tissue extraction with sufficient strength and sharpness for clinical use.

Conclusions:

  • Electroplated nickel micro-biopsy tools are a cost-effective solution for capsule endoscopes.
  • These tools enable precise tissue sampling for diagnosis and cancer detection.
  • The fabrication method is scalable for mass production and integration with endoscopic devices.