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Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

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Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Acute Coronary Syndrome III: Diagnostic Studies01:30

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Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
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Acute Coronary Syndrome V: Nursing Management01:26

Acute Coronary Syndrome V: Nursing Management

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Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
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Angina II: Classification01:27

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Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
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Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

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Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
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Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

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Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
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Author Spotlight: Advancing Cardiovascular Imaging - Introducing the Spatially Weighted Calcium Score for Early Disease Detection
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The CHA2DS2-VASC Score Predicts Mortality in Patients Undergoing Coronary Angiography.

Nicholay Teodorovich1, Gera Gandelman1, Michael Jonas1

  • 1Kaplan Medical Center, Rehovot and the Hebrew University, Jerusalem 7661041, Israel.

Life (Basel, Switzerland)
|October 28, 2023
PubMed
Summary

The CHA2DS2-VASc score predicts mortality in patients undergoing coronary angiography. A higher score (≥4) independently indicates increased mortality risk, suggesting its use in initial patient screening.

Keywords:
CHA2DS2-VASC scorecoronary angiographymortalityoutcomes

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Area of Science:

  • Cardiology
  • Clinical Risk Stratification

Background:

  • The CHA2DS2-VASc score is established for predicting thromboembolic risk in atrial fibrillation (AF).
  • Its utility in predicting mortality in patients undergoing coronary angiography is not well-defined.

Purpose of the Study:

  • To investigate the CHA2DS2-VASc score's ability to predict mortality in patients undergoing coronary angiography.

Main Methods:

  • Prospective study of 990 patients undergoing coronary angiography.
  • Patients stratified by CHA2DS2-VASc score (<4 vs. ≥4).
  • Kaplan-Meier analysis and Cox regression modeling used to assess mortality risk.

Main Results:

  • A CHA2DS2-VASc score ≥4 was associated with significantly higher all-cause mortality (38.7% vs. 13.1%, p < 0.0001).
  • This association persisted across subgroups including those with and without AF, varying LVEF, and renal function.
  • An elevated CHA2DS2-VASc score (≥4) was an independent predictor of mortality (HR 2.12, p = 0.001).

Conclusions:

  • The CHA2DS2-VASc score is a simple and reliable predictor of mortality in patients undergoing coronary angiography.
  • It can be utilized for initial screening to identify high-risk individuals.