Jove
Visualize
Contact Us

Related Experiment Videos

Thyrotoxicosis: changing trends in treatment.

J Sheldon, D J Reid

    Annals of the Royal College of Surgeons of England
    |September 1, 1986
    PubMed
    Summary

    Thyrotoxicosis treatment has evolved, favoring surgery for severe cases and thyroid ablation with radioiodine. Conventional carbimazole courses and standard radioiodine doses are used less frequently due to unpredictable responses and insufficient effect.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    First steps in the standardization of immunoglobulin IgG myeloperoxidase-anti-neutrophil cytoplasmic antibody measurements.

    Clinical and experimental immunology·2015
    Same author

    Using UHF proximity loggers to quantify male-female interactions: a scoping study of estrous activity in cattle.

    Animal reproduction science·2014
    Same author

    Laboratory investigation of anaphylaxis: not as easy as it seems.

    Anaesthesia·2014
    Same author

    International standards for IgG and IgM anti-β2glycoprotein antibody measurement.

    Lupus·2014
    Same author

    The efficacy of a vitamin D(3) metabolite for improving the myofibrillar tenderness of meat from Bos indicus cattle.

    Meat science·2011
    Same author

    Observing signs of pain in relation to self-injurious behaviour among individuals with intellectual and developmental disabilities.

    Journal of intellectual disability research : JIDR·2011
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Area of Science:

    • Endocrinology
    • Thyroid disease management
    • Internal medicine

    Background:

    • Thyrotoxicosis management requires careful consideration of patient age, severity, and treatment efficacy.
    • Previous treatment protocols involved prolonged carbimazole courses and conventional radioiodine doses.

    Purpose of the Study:

    • To review and modify treatment approaches for thyrotoxicosis based on a 14-year experience.
    • To optimize therapeutic strategies for improved patient outcomes in thyrotoxicosis.

    Main Methods:

    • Retrospective review of thyrotoxicosis treatment over 14 years.
    • Analysis of treatment modifications including surgical intervention, radioiodine therapy, and carbimazole use.

    Main Results:

    • Reduced use of prolonged carbimazole therapy, with increased recommendation for surgery in young and middle-aged severe thyrotoxic patients.
    • Decreased frequency of conventional therapeutic radioiodine doses due to unpredictable responses.
    • Increased utilization of thyroid ablation with radioiodine and identification of frequently suboptimal 'ablative' doses.

    Conclusions:

    • Treatment strategies for thyrotoxicosis have been refined, emphasizing surgery and more aggressive radioiodine ablation.
    • Current approaches aim to improve efficacy and predictability in managing thyrotoxicosis.
    • Further adjustments in radioiodine dosing may be necessary for optimal thyroid ablation.

    Related Experiment Videos