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Published on: May 11, 2015
Clinical Utility of Patient-Reported Outcome Instruments in the Management of Pulmonary Hypertension: A Systematic
Scott W Rose1, Kristin B Highland2, Anita A Kelkar3
1Sections of Critical Care and Cardiovascular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Patient-reported outcome measures (PROM) for pulmonary hypertension (PH) show promise. EmPHasis-10 offers strong psychometric properties and feasibility for clinical use in pulmonary arterial hypertension (PAH) and chronic thromboembolic disease (CTEPH).
Area of Science:
- Pulmonary Medicine
- Clinical Outcomes Research
- Health Outcomes Measurement
Background:
- Disease-specific patient-reported outcome measures (PROM) offer greater sensitivity and specificity for detecting clinical change in pulmonary hypertension (PH).
- Instruments for PH, including pulmonary arterial hypertension (PAH) and chronic thromboembolic disease (CTEPH), are emerging but not yet widely used in routine care.
- This systematic review evaluates the psychometric properties and clinical utility of these PH-specific PROM.
Conclusions:
- EmPHasis-10 exhibits strong psychometric properties and high feasibility for clinical application in PH.
- Further research is necessary to assess the integration of PROM into the routine clinical care of PH patients.
- Disease-specific PROM like emPHasis-10 are valuable tools for assessing clinical change in PH.
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