Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
2.5K
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

10
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
10
Respiratory System Abnormal Finding I: Inspection and Percussion01:30

Respiratory System Abnormal Finding I: Inspection and Percussion

279
Respiratory system abnormalities are a significant concern in healthcare due to their potential to indicate underlying severe conditions like Chronic Obstructive Pulmonary Disease (COPD), asthma, and pneumonia. These abnormalities can often be detected through physical examination methods like inspection and percussion.
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...
279
Pneumothorax-II01:27

Pneumothorax-II

170
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
170
Flail Chest-II01:26

Flail Chest-II

184
Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
184
Physical Assessment of the Respiratory Tract II: Inspection01:27

Physical Assessment of the Respiratory Tract II: Inspection

310
Physical assessment of the respiratory tract through inspection is a crucial step in understanding the patient's respiratory health. It provides insights into the functioning of the respiratory system, the musculoskeletal structure, and even the patient's nutritional status. This comprehensive approach involves observing several vital aspects: chest configuration, breathing patterns, respiratory rates, skin color, and use of accessory muscles.
Chest Configuration
The chest configuration...
310

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Can machine learning improve on the early prediction of upper limb recovery after stroke?

Journal of neuroengineering and rehabilitation·2025
Same author

ADRB2 genotype-guided treatment for childhood asthma: Cost analysis of the PUFFIN and PACT trials.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology·2025
Same author

Optimizing care for children with difficult-to-treat and severe asthma through specialist paediatric asthma centres: expert practical experience and advice.

BMC pediatrics·2024
Same author

Antihypertensive drug concentration measurement combined with personalized feedback in resistant hypertension: a randomized controlled trial.

Journal of hypertension·2023
Same author

Prediction model for hypertension in first decade after pre-eclampsia in initially normotensive women.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2023
Same author

Accelerometer-derived physical activity and sedentary time and cardiac biomarkers: The Maastricht Study.

Frontiers in cardiovascular medicine·2023

Related Experiment Video

Updated: Jul 12, 2025

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
02:09

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Published on: April 12, 2024

621

Chest computed tomography in severe bronchopulmonary dysplasia: Comparing quantitative scoring methods.

S Fontijn1, S J A Balink2, M Bonte2

  • 1Post-graduate School of Paediatrics, University of Modena and Reggio Emilia, Modena, Italy.

European Journal of Radiology
|October 28, 2023
PubMed
Summary

The manual Hounsfield unit (HU) method and PRAGMA-BPD score show excellent reproducibility for quantifying lung damage in bronchopulmonary dysplasia (BPD). These methods accurately assess CT abnormalities in infants with BPD.

Keywords:
(semi-) automatedBirth weightBronchodilator useBronchopulmonary dysplasiaChest-computed tomography scanChildQuantitative scores

More Related Videos

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

50.0K
Point-of-Care Lung Ultrasound in Adults: Image Acquisition
09:17

Point-of-Care Lung Ultrasound in Adults: Image Acquisition

Published on: March 3, 2023

6.1K

Related Experiment Videos

Last Updated: Jul 12, 2025

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
02:09

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function

Published on: April 12, 2024

621
Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

50.0K
Point-of-Care Lung Ultrasound in Adults: Image Acquisition
09:17

Point-of-Care Lung Ultrasound in Adults: Image Acquisition

Published on: March 3, 2023

6.1K

Area of Science:

  • Pulmonary Medicine
  • Radiology
  • Neonatology

Background:

  • Bronchopulmonary dysplasia (BPD) is a common complication in extremely preterm infants, often associated with structural lung abnormalities.
  • Accurate quantification of lung damage in BPD is crucial for patient management and research.

Purpose of the Study:

  • To evaluate three new Hounsfield unit (HU) based chest-CT scoring methods for quantifying lung damage in BPD.
  • To assess the intra- and inter-observer variability of these methods.
  • To compare the HU methods with the established Perth-Rotterdam-Annotated-Grid-Morphometric-Analysis (PRAGMA)-BPD score and clinical data.

Main Methods:

  • Chest CT scans from infants with severe BPD were analyzed at a median of 7 months corrected age.
  • Quantification of hyper- and hypo-attenuated regions was performed using PRAGMA-BPD and three HU-based methods (automated, semi-automated, manual).
  • Reproducibility was assessed using intraclass correlation coefficients (ICC) and Bland-Altman plots; correlations with clinical data were evaluated using Spearman rank correlation.

Main Results:

  • The manual HU method and PRAGMA-BPD demonstrated excellent intra- and inter-observer reproducibility (ICCs 0.80-0.97).
  • The manual HU method showed high correlation with PRAGMA-BPD for both hyper- (ρ=0.92) and hypo-attenuation (ρ=0.79).
  • Automated and semi-automated HU methods exhibited poorer correlation, especially for hypo-attenuation.

Conclusions:

  • The manual Hounsfield unit (HU) method and PRAGMA-BPD score offer the best reproducibility for quantifying CT abnormalities in BPD.
  • These findings support the use of the manual HU method as a reliable tool for assessing lung damage in BPD.