Rapid enzymatic activity model (REAM) to decipher the toxic action of per- and polyfluoroalkyl substances
Precious Obiako1, Amanda Sevcik1, Christie M Sayes1
1Department of Environmental Science, Baylor University, Waco, TX, 76798, USA.
Abstract:
Per- and polyfluoroalkyl substances (PFAS) have been identified as emerging contaminants and human exposure to these substances is a rising public health concern. We have developed a rapid enzymatic activity model (REAM), which can serve as a cell-free screening tool that elucidates possible mechanisms of toxic action inexpensively and quickly for these and other environmentally relevant chemicals.
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