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Published on: April 13, 2022
Characteristics of amino acid metabolism in colorectal cancer
Fen Xu1, Hong-Liang Jiang1, Wei-Wei Feng1
1Department of Gastroenterology, Xinhua Hospital Affiliated to Dalian University, Dalian 116000, Liaoning Province, China.
Abstract:
In recent years, metabolomics research has become a hot spot in the screening and treatment of cancer. It is a popular technique for the quantitative characterization of small molecular compounds in biological cells, tissues, organs or organisms. Further study of the tumor revealed that amino acid changes may occur early in the tumor. The rapid growth and metabolism required for survival result in tumors exhibiting an increased demand for amino acids. An abundant supply of amino acids is important for cancer to maintain its proliferative driving force. Changes in amino acid metabolism can be used to screen malignant tumors and improve therapeutic outcomes. Therefore, it is particularly important to study the characteristics of amino acid metabolism in colorectal cancer. This article reviews several specific amino acid metabolism characteristics in colorectal cancer.
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