Related Experiment Video
Updated: Jul 12, 2025
10:28
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
11.1K
Advancements in Understanding Gastric Cancer: A Comprehensive Review
Khizer K Ansari1, Vasant Wagh2, Azeem I Saifi3
1Medicine and Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.
Cureus
|October 30, 2023
Summary
This review summarizes recent gastric cancer (GC) research, covering epidemiology, molecular insights, biomarkers, and novel therapies like immunotherapy. It highlights the importance of the tumor microenvironment for improving GC treatment outcomes.
Area of Science:
- Oncology
- Gastroenterology
Background:
- Gastric cancer (GC) remains a significant global health challenge.
- Understanding GC's complexity is crucial for improving patient outcomes.
Purpose of the Study:
- To provide a comprehensive review of recent advancements in gastric cancer research.
- To synthesize current knowledge on GC epidemiology, pathogenesis, diagnosis, and treatment.
Main Methods:
- Literature review of recent studies on gastric cancer.
- Analysis of epidemiological data, molecular mechanisms, and therapeutic strategies.
- Examination of diagnostic and prognostic biomarkers, surgical procedures, and imaging modalities.
Main Results:
- Recent research offers deeper insights into GC pathogenesis and the tumor microenvironment.
- Novel biomarkers and therapeutic approaches, including immunotherapy, show promise.
- Advances in surgical techniques and imaging aid in diagnosis and staging.
Conclusions:
- A comprehensive understanding of GC, including its molecular underpinnings and microenvironment, is essential for effective treatment.
- Further research is needed to address knowledge gaps and enhance GC management strategies.
- This review consolidates current knowledge and identifies future research directions for improving gastric cancer care.
Related Concept Videos
02:07Tumor Progression
6.3K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.3K
01:27Gastritis-I: Introduction and Types
478
Gastritis, defined by the inflammation or irritation of the stomach lining or gastric mucosa, manifests in several distinct forms: acute, chronic, reactive, and a specific subtype known as autoimmune metaplastic atrophic gastritis.
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
478